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Serious reactions are rare but possible
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Examples include insulin for diabetics, as well as glucagon-like peptide-1 agonists such as semaglutide-based Ozempic and Wegovy that can be used for weight loss
This peptides origins in stomach proteins also make it very stable and resistant to enzyme digestion and hydrolysis
When symptoms do occur in the context of high B12, they are usually attributable to an underlying condition rather than the elevated vitamin itself
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