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PE135000: α-GalNAc-PEG3-Thiol label-new Cys is conjugated at the

SKU: 76516919012
4.1
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Description

Cys is conjugated at the N-terminal of peptide sequence

This compound provides a lactose (Galβ1-4Glc) building block for glycoconjugate synthesis and the construction of probes for galactose-recognizing proteins

C24H27NO9 / 473

/ MUC1(126-149)-STn(131) / Mucin1

82 / MUC4 (UniProt ID A0A0G2JMX1) synthetic peptide fragment (Thr1179-Asp1194

PE135000: α-GalNAc-PEG3-Thiol label-new Cys is conjugated at theC14H27NO8S 369. 43 An D N acetylgalactosamine (GalNAc) ligand equipped with a free thiol through a hydrophilic PEG3 spacer. The thiol reacts with maleimides to form stable thioether conjugates or with other thiols to form disulfide bonds; it is also compatible with thiol gold chemistry for surface immobilization. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor

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