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6-tri-O-acetyl-β-D-galactopyranosyl-(1→3)-2-N-acetamido-2-deoxy-4
and other debranching α-glucosidases)
followed by cleavage of the α-glycosidic bond by α-L-iduronidase (IDUA) to release 4-methylumbelliferone
41 / A β-D-lactose ligand equipped with a thiol-functionalized linker through a short ethyl spacer
enzymatic cleavage releases 4-nitrophenol
GA421000: Fmoc-Ser(Gal(Ac)4-β-D)-OH Pack Size:250 mg 6-tri-O-acetyl-β-D-galactopyranosyl-(1→3)-2-N-acetamido-2-deoxy-4C32H35NO14 657. 62 An Fmoc protected L serine building block carrying a D galactose residue, designed for solid phase peptide synthesis (SPPS) of glycopeptides. The N Fmoc group is removed under standard base conditions (piperidine) during chain elongation, while the free carboxylic acid is available for coupling to the growing resin bound peptide. The sugar hydroxyl groups are protected as four acetate esters (Ac4), which keep the glycan inert during
