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with the sugar hydroxyl groups protected as acetate esters
2-[2-(2-Azidoethoxy)ethoxy]ethyl α-D-mannose-6-phosphate
/ β-Glc-PEG3-Amine / β-Glc-PEG3-NH2
89 / Chronic Kidney Disease / rac-Cinacalcet-d3
free acid) L-serine glycoamino acid carrying a Galβ1-3GalNAcα disaccharide
PE131010: β-GalNAc-PEG3-Alkyne label-new with the sugar hydroxyl groupsC17H29NO9 391. 41 A D N acetylgalactosamine (GalNAc) ligand equipped with a terminal alkyne through a hydrophilic PEG3 spacer. The alkyne couples to azide functionalized partners via copper catalyzed azide alkyne cycloaddition (CuAAC), forming stable 1,2,3 triazole linkages. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor (ASGPR), which is highly expressed on
