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Through the application of PTE and Patent Term Adjustment (PTA), Novo Nordisk succeeded in pushing the expiration of the 343 patent to December 5, 2031
injections of 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages), 300 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 8 mice and n = 4 cages) for 14 days
Symptoms that require immediate medical attention Fever of 100.4 degrees Fahrenheit or higher
Journal reference: Emptage, I., Kozmr, S., Cobham-Wilson, A., Sousa, B., Sugden, K., Wheeler, L., Llewellyn, C., Makaronidis, J., Bulik, C., Solmi, F
Skin sensitivity and injection site reactions have been reported at rates comparable to other injectable peptides
