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Current opinion in pharmacology, 7(4), pp.355-359
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E3 was divided into two segments, E3-N (1200 aa, the RING domain) and E3-C (201650 aa)
Some pilot studies suggest preservation of brain metabolism, while others have not demonstrated meaningful cognitive improvement
In this trial, at 60 weeks, the exenatide group showed a significant improvement in MDS-UPDRS Part III scores compared to the placebo group among the 62 recruited patients (80)
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