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5.5 Acute Kidney Injury Due to Volume Depletion There have been postmarketing reports of acute kidney injury in some cases requiring hemodialysis, in patients treated with semaglutide
Discontinuation rates differ based on underlying medical conditions
The improvement comes through weight loss and metabolic improvement
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The FDA includes a warning about medullary thyroid carcinoma and advises against use in individuals with a family history of the disease or a family history of MEN 2
[18] Lactation studies demonstrate that maternal injections modestly elevate breast-milk B12 concentrations without adverse infant outcomes, supporting compatibility with breastfeeding while underscoring the need for maternal repletion to prevent neonatal deficiency
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