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Model building and refinement The model building for the non-active class was initiated by individually fitting rigid-body components of the LBD extracted from the BPAM344-, and ConA-bound GluK2 structure (PDB code 9B36), and the TMD and ATD from the BPAM344 bound GluK2 structure (PDB code 8FWQ) into the cryo-EM map using Chimera
doi:10.1001/archgenpsychiatry.2009.60
These findings may add to the mechanisms of GLP-1 RA-induced weight loss
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The award funds research until December 31, 2021
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