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Then theres the placebo effect
You start at the full therapeutic dose from the first injection and maintain it for all 4
Maybe and maybe not
Its common to start treatment for a significant vitamin B12 deficiency with weekly intramuscular shots (1000 micrograms of vitamin B12)
If you prefer evening supplementation and experience no sleep disturbances, there is no medical reason to change your routine
Efficacy of Different Routes of Vitamin B12 Supplementation for the Treatment of Patients with Vitamin B12 Deficiency: A Systematic Review and Network Meta-Analysis. Irish Journal of Medical Science, 17 Jan
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