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When designing research protocols for topical GHK-Cu, we recommend the following best practices: Application to Clean Skin: Ensure the skin is clean and dry before application to facilitate optimal absorption

However, as reported concentrations of GSH are in the range of 0.2 mol/l in CSF and 1 mmol/l in brain tissue, 7 GSH in CSF would not appreciably change the MRS determination of GSH in brain tissue

doi: 10.1038/s41584-023-01021-4 39 LopesEBPFilibertiAHusainSAHumphreyMB

Patients who already have exceptionally high pyridoxine levels or signs of pyridoxine toxicity (such as sensory neuropathy) should not continue to receive high-dose supplementation until those symptoms resolve

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Dissolve the powder in the water or serum phase of your recipe for optimal integration