Excessive accumulation of lipid droplets within these cells can trigger lipotoxicity, promoting fibrosis development (13)
As of 2022, it is included in WADAs prohibited substances list
AOD 9604's lipolytic activity is blunted by insulin
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Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme [PMID: 34260721] Laboratory literature summary: Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD)