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Limited clinical data supporting the long-term safety of nasal administration
That's plausible, but it's based on limited human pharmacology research, not large clinical trials
The Australasian College of Dermatologists told ScienceAlert it "shares the concerns of the broader medical community about the use of melanotan II"
Patients are widely reporting that their doctors are willing to prescribe GLP-1s for substance use disorders upon request, reflecting the broad safety of the medication class
These findings suggest that the addition of exercise to GLP-1 RA treatment is an effective weight loss strategy while preserving bone health, the researchers wrote
A phase 2 trial with Retatrutide also noted slight increase in heart rate (around 10bpm) after 24 weeks, but that this increased heart rate subsides over time
