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In a dedicated Phase 2a liver fat trial published in Nature Medicine, retatrutide produced dose-dependent reductions in liver fat that are unlike anything previously seen

The manufacturer, Novo Nordisk offers a Wegovy Savings Card program to help people save money with or without insurance

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As of 2025, retatrutide has not received FDA approval

The SELECT trial establishing semaglutides 20% reduction in major adverse cardiovascular events has converted GLP-1 receptor agonists from single-indication obesity drugs into foundational chronic disease therapeutics demanding continuous prescription renewal

doi:10.1136/jnnp.74.1.70 20