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Although the small number of simple size (n=15), no genomic alterations at baseline or at progression seem to be associated with Dato-DXd response

Gastrointestinal adverse effects are the most common side effects of semaglutide, with rates varying by product and dose

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In both analyses, the incremental benefits of semaglutide 2.4 mg against D&E in avoiding cardiovascular events were marginal, which may be explained by these being lower risk populations

The central composite endpoint was the period that starts from randomization to the first occurrence of a MACE or major adverse cardiovascular event such as cardiovascular collapse, non-fatal stroke, and non-fatal myocardial infarction