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Importantly, the use of radiotherapy in conjunction with Gln metabolism inhibitors does not produce toxic effects on non-malignant prostate cells

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demonstrated in vitro the anti-leukemic activity of the novel CPT1A reversible inhibitor ST1326 on leukemia cell lines and primary cells obtained from patients with hematologic malignancies, which induces cell growth arrest, mitochondrial damage, and apoptosis 32

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This has contributed to a significant increase in demand for and interest in GLP-1RAs around the world

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