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The primary function of the HSD11B1 encoded enzyme is to reduce the 11-oxo groups in cortisone and 11-dehydrocorticosterone to the active glucocorticoids, cortisol and corticosterone, respectively

GLP-1RAs were also efficacious as adjunctive therapies [e.g., in combination with nicotine replacement therapies (NRTs)]

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Cai Y, Liu X, Zhang W et al (2013) Clinical trial of etanercept tapering in juvenile idiopathic arthritis during remission

Zhao HB, Jia L, Yan QQ, Deng Q, Wei B