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The Weibull parameter is used to predict the time to onset and can serve to refine pharmacologic management thinking for patients in clinical practice (Mazhar et al., 2021

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skin feels softer Oily/Acne-Prone: calmer skin with slight smoothing of surface texture Normal/Combination: subtle glow and balanced texture Weeks 34: Cellular Turnover All skin types: increased cellular turnover, leading to firmer texture Dry/Sensitive: stronger skin barrier, improved moisture retention, gentle plumping Oily/Acne-Prone: faster healing of minor breakouts, smoother appearance Normal/Combination: noticeable elasticity and recovery from minor stressors Weeks 68+: Structural Improvements All skin types: firmer, more resilient skin

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Forlani from T BridgeBV Tech S.p.A and Igor Monti from Istituto di Ricerche Farmacologiche Mario Negri IRCCS who kindly assisted us with data collection

The compound showed remarkable potency in promoting spinogenesis (dendritic spine formation) and synaptogenesis in hippocampal neurons