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Additionally, GLP-1 (50 nM) protected against synaptic dysfunction in the rat hippocampus induced by injection of lipopolysaccharide (LPS) (Iwai et al., 2014)

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Managing Side Effects While Optimizing Your Dose Nausea is the most common side effect during dose escalation, typically occurring within the first 12 weeks at each new dose level

She now works out for about two hours six days a week by hiking, doing cardio or resistance training

Current nutrition recommendations advise that patients with AKI receive additional protein supplementation to address the hypercatabolic state

For individuals who tolerate tirzepatide well and do not require additional metabolic support, plain tirzepatide may be the best choice