You topped out at 0.5mg or 1mg because every increase brought unbearable gastrointestinal distress
It is often used for medical purposes to stimulate the production of growth hormones in the body
For instance, one study found that weekly treatment with semaglutide reduced risk of a combination of stroke, heart attack, and death from cardiovascular causes by 20% compared to a placebo
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Given the poor bioavailability of oral NAD+ and its precursor vitamins through supplements (and why most wellness supplements have limited benefit), IV or subcutaneous routes are necessary to achieve the serum concentrations observed in the published research
Researchers are still studying the connection, but some case reports suggest symptoms may become more noticeable after dose increases