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17 Its structure, which is primarily GIP sequence-based, includes a C20 fatty di-acid acyl chain that extends the duration of action, thereby allowing once-weekly subcutaneous administration
That trial (announced in 2023) is the first to prove that treating obesity pharmacologically can prevent cardiovascular events , a groundbreaking concept
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J Immunol 204:16 Wei P, Yang Y, Ding Q, Li X, Sun H, Liu Z et al (2016) Oral delivery of Bifidobacterium longum expressing -melanocyte-stimulating hormone to combat ulcerative colitis
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