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Retatrutide, a newer triple hormone agonist, remains primarily in clinical development but represents emerging GLP-1 class expansion
Dynamic shifts in the composition of resident and recruited macrophages influence tissue remodeling in NASH
The glucagon receptor activation adds metabolic benefits including increased energy expenditure, but also introduces different safety considerations
Who Should NOT Take GLP-1s Personal or family history of medullary thyroid carcinoma (MTC)
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