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Quick Answer: Semaglutide may cause or worsen acid reflux symptoms in some patients by delaying gastric emptying, which increases intragastric pressure and can lead to retrograde flow of stomach contents into the esophagus

One major study published in early 2025, which followed over 351,000 adults, found no statistically significant increase in the long-term risk of thyroid cancer for those taking GLP-1 medications compared to those on other diabetes drugs

Single-cell RNA sequencing analysis revealed that the lipid oxidation activity of keratinocytes was closely related to the Th22/Th17 pathway, and lipid peroxidation in keratinocytes was also found to be enhanced during the course of psoriasis (Shou et al., 2021)

(2) preventing activation of the latent complex, for example, with agents such as apitegromab and trevogrumab

Wegovy contains semaglutide