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Generally speaking: Initial antioxidant benefits may begin within 24 weeks Skin brightness improvements may appear within 612 weeks More visible changes often develop over 36 months The body first prioritizes essential functions like detoxification and cellular repair

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Ethics declarations Competing interests The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Sang-Ku Yoo has patent Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease issued to US9783551B2