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FAQ Has FOXO4-DRI ever been tested in a human?+ No
Sadly, the control group didnt receive anything
In the final round of PACE, we increased the evolution substrate to a longer 65-residue region, GD_L (Val 222Asp 286), to better reflect the native IDL context
The possible reason for the same may be attributed to minor differences in the autoprocessing microenvironments and active structural conformations of different bacterial GGTs
The absence of safety data in these populations should inform clinical decision-making and prescribing practices
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