It does this primarily by regulating nitric oxide, a molecule that controls how blood vessels expand and contract (Seiwerth et al., 2018)
Additionally, by promoting healing of tissues, it might indirectly alleviate pain that stems from chronic injuries or inflammation
NAD supplements may help restore levels in the body, which is why interest has exploded in recent years, says Kathleen Jordan, MD, Chief Medical Officer at Midi Health
Regulatory agencies require extensive clinical evidence before approval, and the absence of such data means safety and effectiveness remain uncertain
Elizabeth Rebello of the University of Texas MD Anderson Center
It is also explored for its potential role in supporting growth hormone activity and reducing oxidative stress in neural tissue