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First described in the early 19th century, the pigment was initially thought to be melanin, but it was later found to be lipofuscin deposited in macrophages within the lamina propria as a result of apoptosis

Theres tremendous policy interest in expanding Medicare coverage for GLP-1s to include patients trying to lose weight, Klebanoff said

It is important to note that individual responses may vary, and some patients might experience different lipid changes based on their baseline metabolic status, concurrent medications, dietary habits, and genetic factors

This is an area where policy details matter

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In other settings (like surgical cohorts), it may appear more often simply because more tissue is being sampled and examined carefully