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The FDA summarized its ongoing evaluation of reports involving suicidal thoughts or actions in people taking GLP-1 receptor agonists

She advises doctors to be proactive in monitoring the risk in GLP-1 patients, especially in postmenopausal women and men over age 50 who would already be at higher risk of bone loss due to their age

MK-677 also increases water retention, which can mask fat loss on the scale

Renal function generally improves with GLP-1 agonists in diabetic patients, likely due to improved glycemic control and reduced intraglomerular pressure

A mild fruity urine odor can be expected if the body is in a state of nutritional ketosis , which happens during fasting, low-carb diets, or weight loss

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