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Similarly, people with lower levels of stomach acid may also have a difficult time releasing the vitamin for absorption

By dosage, the mean changes were: 500 mcg: 127% 750 mcg: 176% (single study) 1,000 mcg: 280% 1,500 mcg: 310% 2000 mcg: 260% 5,000 mcg: 62% While 1,500 mcg of vitamin B12 showed the highest average increase, the effect plateaued or declined at higher doses, suggesting a possible saturation of absorption pathways

Slow vs fast titration is compared at matched final maintenance dose for the 4 mg and 8 mg cohorts

Therefore, vitamin B12 should only be injected by a health care professional who is prepared to provide first aid immediately

Diet-related: If your vitamin B12 deficiency is caused by a lack of vitamins in your diet, you may be prescribed vitamin B12 tablets to take every day between meals

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