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J Physiol.
These drugs operate like semaglutide, replicating the physiological effects of GLP-1
Yet, these benefits are offset by higher costs, fragmented supply chains, and limited familiarity among formulators
Before starting any GLP-1 compoundwhether semaglutide, tirzepatide, or a dual formulationunderstanding your baseline triglyceride level, lipid panel, and metabolic predispositions can help your provider determine whether triglyceride improvement is a realistic goal and what timeline to expect
Realistic expectations are important
GLP-1 medicines in neuro- and cardiovascular inflammation Microglia secrete pro-inflammatory cytokines upon activation, stimulating nearby reactive astrocytes and amplifying local neuroinflammation
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