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Conversely, valproate may displace certain protein-bound drugs (e.g., phenytoin, carbamazepine, warfarin, and tolbutamide) [seeDrug Interactions (7.2)for more detailed information on the pharmacokinetic interactions of valproate with other drugs ]

Cabungcal JH, Steullet P, Kraftsik R, Cuenod M, Do KQ

doi: 10.1111/cpr.12576 121

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To examine the similarity of peptides predicted by different models within each potency profile, we used PCA, considering the 500 one-hot-encoded sequences generated across all five compared models, the wild-type peptideshGCG and hGLP-1and their single-step mutants (551 hGCG and 570 hGLP-1), such that the projection was computed for an array [1,621 21 L ]