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The AWARD-7 trial, which was the first clinical trial among moderate-to-severe CKD and T2DM displayed convincing protective effects on eGFR after treatment with GLP-1RAs [46]

Ongoing large-scale prospective studies and post-marketing surveillance are needed to further refine risk estimates and inform evidence-based clinical guidance for patients at higher baseline risk

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It contains additional components that may provide extra benefits for weight management and overall health

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Common side effects of Semaglutide tablets Nausea Vomiting Diarrhea Constipation Abdominal pain Common Side effects of Semaglutide injection Nausea Gastrointestinal discomfort Pain and swelling or redness at the injection site The side effects of injectable semaglutide are milder given that the rate of release of the drug is slower compared to the oral form