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The pancreatic effects of GLP-1 receptor activation in humans appear to be complex and likely influenced by individual patient factors, pre-existing pancreatic health, and concurrent metabolic conditions

Understanding these mechanisms helps clinicians counsel patients on expected sensations versus concerning reactions requiring further evaluation

As you lose weight, your TDEE drops, so a deficit set at your starting weight gets smaller over time

doi:10.3945/ajcn.2009.28449C 10

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