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2.6.7 Mitotracker staining assay Mitochondrial toxicity assessment was performed by the Laboratory 1 using MitoTracker Red FM reagent, a cell-permeant dye able to stain active mitochondria in live cells

Gingipain-responsive thermosensitive hydrogel loaded with SDF-1 facilitates in situ periodontal tissue regeneration

Stem Cell-Based Therapies Stem cell-based approaches, with their vigorous advantages, have gained increasing recognition as potential strategies to restore BBB and BSCB integrity in the context of traumatic injury and stroke [265]

A 2020 review on the safety of BPC-157 in preclinical (animal) studies states that the peptide did not show any test-related effects in the single-dose toxicity study and that it was well tolerated in repeat-dose evaluations.16 Other animal studies and reviews mention that BPC-157 has no reported toxicity or that it was without a lethal dose in toxicology studies.14 17 Even the authors of a small human study on BPC-157 for interstitial cystitis note that no one dropped out of the study, and no adverse events were reported.18 We want to highlight that most of the relevant studies have been conducted on animals, and more human research is needed

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