The researchers wrote in the journal JAMA Ophthalmology : We observed an increased NAION risk with semaglutide exposure relative to non-exposure. They also found an increased risk in people using semaglutide compared to those using other diabetes drugs, like empagliflozin and sitagliptin
Acta Gastroenterol Belg 75:240244 Joy TR, McKenzie CA, Tirona RG et al (2017) Sitagliptin in patients with non-alcoholic steatohepatitis: a randomized, placebo-controlled trial
The effectiveness of the drug may decrease, and it may not provide the intended benefits
Lyophilized & packaged in America Freeze-dried into sterile, UV-resistant glass vials and packaged in the USA
Novo Nordisks Indian patent on semaglutide expires in March, opening the door for the countrys vast generic drug industry to enter the market
Heat, oxygen, UV light, and contamination accelerate peptide degradation, which can reduce potency even if the peptide still looks unchanged