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The pancreatic effects of GLP-1 receptor activation in humans appear to be complex and likely influenced by individual patient factors, pre-existing pancreatic health, and concurrent metabolic conditions
E., Bauer, J
GLP-1 is made in the gut and helps: Trigger insulin release Lower glucagon levels (which raise blood sugar) Slow digestion Increase feelings of fullness GIP is made in the small intestine and helps: Stimulate insulin release after eating Regulate blood sugar and energy Influence appetite and fat storage These medications mimic the actions of the bodys natural GLP-1 and/or GIP hormones
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doi: 10.1056/NEJMoa1515920 7 NealBPerkovicVMahaffeyKWde ZeeuwDFulcherGEronduNet al
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