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Wegovy is metabolised through proteolytic degradation, similar to endogenous proteins, without involvement of cytochrome P450 enzymes
This occurs because rapid weight loss can lead to an imbalance in the substances that make up bile, increasing cholesterol levels in bile and reducing the frequency of gallbladder emptying, both of which can contribute to the formation of gallstones
However, it is important to remember that retatrutide is still undergoing clinical trials to establish its long-term safety and effectiveness before regulatory approval is considered
Bejanin A, Schonhaut DR, La Joie R, et al
Peptides do not cause impairment
Also contains sodium metabisulfite 1.5 mg and sodium hydroxide to adjust the pH.
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