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So theyre just taking in less water than everybody else," explains Dr
Specifically, GHK-Cu was found to be least possible to cause skin irritation, while CuCl 2 and Cu(OAc) 2 were found to induce the expression of various skin irritation biomarkers, i.e., IL-1, IL-8, FOSL1, and HSPA1A
PMCID: PMC11228148
The medication is absorbed directly into the bloodstream from subcutaneous tissue, bypassing the gastrointestinal tract, which means food in your stomach does not interfere with absorption
10.1038/nature01921 324
Still, Apovian says that the potential suggested by the retatrutide results is "really fantastic," although she adds that having a variety of weight loss medications is important
