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Extending the lens to major cardiac procedures, Ogawa et al (Ogawa et al., 2025)

Tysnes O, Kenborg L, Herlofson K, Steding-Jessen M, Horn A, Olsen JH, et al

Clinical studies 3 in healthy adult men demonstrate dose-dependent increases in GH/IGF-1, with careful measurement of both baseline and response levels, highlighting the importance of precision

The mechanism may involve multiple effects: enhanced autophagy (cellular cleanup), reduced neuroinflammation, improved mitochondrial energy metabolism, and enhanced BDNF signalling

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Updated reports will be posted here once finalized