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virtually all gray matter areas can be involved including cerebral cortex, hippocampus, deep gray matter nuclei, cerebellum and even spinal gray matter (Calabrese et al., 2015

3DVA performed on the particle stacks from the initial larger dataset revealed that ECL3 is dynamic, consistent with the identification of two slightly differing ECL3 conformations from individual experiments (discussed in more detail below)

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Peripheral blood samples were obtained from each ALS patient and control at two visits separated by 6 months

Normal serum levels may be found in cases of deficiency where myeloproliferative disorders, liver disease, transcobalamin II, or small intestinal bacterial overgrowth are present