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The rationale focuses on local gut effects rather than systemic distribution

Dose and frequency Standard NHS loading is 1mg of hydroxocobalamin on alternate days for up to two weeks, then maintenance every two to three months

Warnings & Storage WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use

For naturally occurring B12 in food, the presence of gastric acid, pepsin, and intrinsic factor is essential for liberation and absorption