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In addition to cytochrome c , other IMS proteins are also mobilized and released into the cytosol where they promote or counteract caspase activation and hence cell death (Munoz-Pinedo et al., 2006)

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The uptake on ascorbate from the lumen of the small intestine as well as its transport into cells is the function of two Na + -dependent vitamin C co-transporters identified as SVCT1 and SVCT2

When serum ferritin levels elevated, it causes exacerbated inflammatory conditions and induces oxidative damage and ferroptosis, along with the decrease in GSH levels (which functions as an oxidative stress regulator), creating a series of reactions that resulted in multiple organ failure, pulmonary injury, and reduced lung capacity in the study Group A