semaglutide or tirzepatide for inflammation Differential Anti-Inflammatory Effects of and in Experimental Diabetes Mellitus Why You Might Tolerate One

Rosenstock reported that body weight loss of almost 17% was achieved with the 8 mg and 12 mg doses at week 36, without showing a plateau

Physical activity enhances weight loss and improves body composition

Over 72 weeks, with lifestyle modifications, losses of 70 to 80 pounds are achievable for high responders

Combination of nivolumab (nivo) + ipilimumab (ipi) in the treatment of patients (pts) with deficient DNA mismatch repair (dMMR)/high microsatellite instability (MSI-H) metastatic colorectal cancer (mCRC): CheckMate 142 study

Disproportionate fatigue is another signal

If your diabetes treatment has changed recently or you are not meeting glycemic targets, testing every three months makes sense until control improves and stabilizes