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Phase 3 trials swapped out the 8 mg dose for 6 mg and 9 mg doses based on the phase 2 data
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doi: 10.1038/s41577-022-00792-3 20
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Cholecystectomy alters bile release patterns and gut hormone signaling, which can affect both GLP-1 tolerability and weight loss response
We still need larger and longer studies, especially in patients with more active lupus, severe lupus nephritis, and complex autoimmune disease
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