Bacteriophage.Jan-Feb 2011;1(1):31-45
Glutathione tackles this at a biological level by: Inhibiting tyrosinase activity to slow down melanin production Shifting melanogenesis from eumelanin (darker) to pheomelanin (lighter) Acting as an antioxidant to reduce the oxidative stress that triggers hyperpigmentation A 2025 systematic review in the International Journal of Dermatology confirms that oral glutathione at doses of 250 mg twice daily and 500 mg once daily showed a significant reduction in melanin index compared to placebo, particularly in sun-exposed areas like the face and wrists
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Gordillo, G
Jindani, R, Rodriguez-Quintero, JH, Olivera, JA, Ries, S, Stiles, BM, Antonoff, MB
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