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Strong target identification normally requires orthogonal evidence such as direct binding, receptor-specific functional assays, selective antagonism, genetic loss of function, rescue experiments, and biophysical or chemical target-engagement analysis

Animal studies on cut Achilles tendons show that BPC-157 accelerates recovery

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There is a similar beneficial effect in the rats with the Pringle maneuver, ischemia, reperfusion, and suprahepatic inferior caval vein occlusion (BuddChiari syndrome) (Kolovrat et al., 2020)