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Topical application uses 1-2% concentration in serums applied daily

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R-lipoic acid is the biologically active isomer that may offer higher potency and better cellular uptake

Megerian MF, Kim JS, Badreddine J, Hong SH, Ponsky LE, Shin JI, Ghayda RA (2023) Melatonin and prostate cancer: Anti-tumor roles and therapeutic application

Sleep Architecture Modulation: As its namesake suggests, it induces SWS sleep and Delta Sleep