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For Hashimoto's patients, this discontinuation requires careful planning because: Thyroid hormone requirements increase significantly during pregnancy (typically 25-50% higher) Weight regain after GLP-1 discontinuation will change levothyroxine requirements again Optimal thyroid function before conception is critical for fetal brain development If you discover you are pregnant while on a GLP-1 medication , stop the medication immediately and contact your healthcare provider for urgent thyroid function testing and levothyroxine dose adjustment

There are individual differences between medications but the fatigue mechanism is similar across the class

While not a substitute for targeted Lyme therapies, it may support immune stabilization during recovery

2007 Jan;100(1):49-58

Reconstituted peptides degrade much faster, typically lasting 4 to 12 weeks in the fridge and only 24 to 48 hours at room temperature

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