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Robert Kushner: I haven't seen that paper, but what I can say which I thought you were getting to is that when we look at the categorical weight loss in all these trials, so some people lose 5%, 10%, 20%, 25% over the course of the trial, if you then stop the medication, the individuals who lost the greatest amount of body weight actually are the ones that regain it the quickest
In many of these cases, altered renal function has been reversed with supportive treatment and discontinuation of potentially causative agents
PMC 7823251
Connecticut: Appleton & Lange
This approach helps to minimize the risk of side effects such as gastrointestinal (GI) problems
Srinivasan B, Kolli AR, Esch MB, Abaci HE, Shuler ML, Hickman JJ
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