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Lu J et al

Because CVD is the leading cause of death in patients with type 2 diabetes (T2D), T2D is often referred as a 'cardiovascular disease (CVD)' [1]

Mechanism of Action: an isotopic deuterated isomer of tetrabenazine, where two O-linked methyl groups (O-CH 3 ) of the tetrabenazine molecule have been replaced by 2 trideuteromethyl groups (O-CD 3 )

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2003 The landmark 2003 study by Molinoff, Shadiack, Earle, Diamond, and Quon published in Annals of the New York Academy of Sciences confirmed that PT-141 administration to normal men and patients with erectile dysfunction produced a rapid, dose-dependent increase in erectile activity establishing the foundational clinical pharmacodynamic data for PT-141s erectile research application and confirming that the CNS melanocortin pathway generates erectile responses independently of peripheral vascular mechanisms