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Entry into cells occurs predominantly through ZIP family members located on the plasma membrane, which mediate zinc influx by transporting it from extracellular or vesicular compartments into the cytosol

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3.2 Potential mechanisms of MOTS-c involvement in bone metabolism in osteoblasts 3.2.1 Role of MOTS-c in TGF--mediated osteoblasts MOTS-c has been shown to promote osteoblast differentiation